Axsome Therapeutics, Inc. reported significant financial performance improvements in its quarterly report for the period ending June 30, 2025. The company generated total revenues of $150.0 million for the quarter, a substantial increase from $87.2 million in the same period last year. For the first half of 2025, revenues reached $271.5 million, compared to $162.2 million for the first half of 2024. This growth was primarily driven by increased product sales, particularly from its commercialized products Auvelity, Sunosi, and the recently launched Symbravo, which contributed to a net loss of $48.0 million for the quarter, down from a loss of $79.3 million in the prior year.
The company’s product sales for Auvelity amounted to $119.6 million for the second quarter, up from $65.0 million in the same quarter of 2024. Sunosi sales also increased to $28.9 million from $21.5 million year-over-year. The commercial launch of Symbravo in June 2025 added $0.4 million in sales for the quarter. Axsome's accumulated deficit as of June 30, 2025, stood at $1.23 billion, reflecting ongoing investments in product development and commercialization.
In terms of operational developments, Axsome has expanded its commercial infrastructure, including a sales force to support the marketing of its products. As of July 28, 2025, the company employed 846 full-time staff, a reflection of its growth strategy. The company has also entered into strategic agreements, such as the Pharmanovia License Agreement, which allows for the commercialization of Sunosi in Europe and certain Middle Eastern markets, further enhancing its market reach.
The company’s financial outlook remains cautious, as it anticipates continued operating losses while investing in the commercialization of its products and the development of its pipeline. Axsome has indicated that it may require additional funding to support its operations, which could involve public or private equity offerings, debt financing, or other strategic arrangements. The company believes its existing cash reserves, totaling $303.0 million as of June 30, 2025, will be sufficient to fund operations for at least the next twelve months, but acknowledges the potential need for further capital to sustain its growth trajectory.
About Axsome Therapeutics, Inc.
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