Charles River Laboratories International, Inc. reported total revenue of $4.0 billion for the fiscal year ending December 28, 2024, a decrease of 1.9% from $4.1 billion in the previous year. The decline was primarily attributed to lower volumes in the Discovery and Safety Assessment (DSA) segment, which faced reduced client spending amid a challenging biopharmaceutical demand environment. Operating income also fell significantly to $227.3 million, down 63.2% from $617.3 million in fiscal 2023, largely due to a $215 million goodwill impairment charge in the Manufacturing segment and restructuring costs.

The company undertook several strategic initiatives during the year, including the acquisition of a controlling interest in Noveprim Group, a supplier of non-human primates, which contributed positively to the Research Models and Services (RMS) segment. RMS revenue increased by 4.7% to $829.4 million, bolstered by higher pricing for small research models. Conversely, the DSA segment saw a revenue decline of 6.3% to $2.45 billion, reflecting a cautious approach from clients regarding early-stage R&D spending. The Manufacturing segment reported a revenue increase of 6.6% to $769.3 million, driven by growth in biologics quality-control testing services.

Operationally, the company reduced its workforce by approximately 8% since the end of 2023 as part of its restructuring efforts to align with current demand levels. As of December 28, 2024, Charles River employed around 20,100 individuals, with a significant portion of its workforce located in North America. The company also reported a backlog of approximately $2.0 billion in the DSA segment, down from $2.5 billion the previous year, indicating a decrease in anticipated future revenue from ongoing and upcoming projects.

Looking ahead, Charles River Laboratories remains focused on optimizing its global footprint and enhancing operational efficiencies to navigate the current market conditions. The company anticipates that the long-term value of strategic outsourcing will continue to drive demand for its services, despite the near-term challenges. Management is committed to implementing further restructuring actions and expects to achieve approximately $225 million in annualized cost savings as a result of these initiatives.

About CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

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