eXoZymes Inc. reported a net loss of $2.37 million for the first quarter of 2026, an increase of 27.7% compared to a net loss of $1.86 million in the same period of 2025. The company's total operating costs rose to $2.39 million, up 22.4% from $1.95 million year-over-year. This increase was primarily driven by a significant rise in research and development expenses, which surged by 95% to $1.12 million, reflecting heightened activity in developing the company's synthetic biology platform. General and administrative costs decreased slightly by 8% to $1.27 million, with notable reductions in professional fees and information technology expenses.
As of March 31, 2026, eXoZymes reported total assets of $4.02 million, a decrease of 32.7% from $5.97 million at the end of 2025. The decline in assets was largely attributed to a significant drop in cash and cash equivalents, which fell by 52.5% to $1.44 million. The company's liabilities also decreased slightly to $2.49 million, down 3.2% from the previous quarter, primarily due to lower long-term operating lease liabilities. However, the company's equity saw a substantial decline of 55% to $1.53 million, driven by the operational losses incurred during the quarter.
In terms of strategic developments, eXoZymes established a wholly owned subsidiary, NCTx LLC, in May 2025, aimed at developing a rare plant-derived compound relevant to metabolic health. The company also announced plans for a public offering of approximately $15 million in common stock, which is expected to support ongoing product development and commercialization efforts. This offering follows a previous initial public offering in November 2024, which raised approximately $15.9 million.
Operationally, eXoZymes has been focusing on expanding its research capabilities and enhancing its product offerings. The company has received significant grant funding, with the Department of Energy contributing 83.2% and the National Institutes of Health providing 16.8% of all grant reimbursements for the quarter. However, the company noted a decrease in grant funding, which impacted its research and development costs. As of March 31, 2026, eXoZymes had a working capital of approximately $507,586, which management indicated may not be sufficient to fund operations for the next twelve months without securing additional financing.
Looking ahead, eXoZymes is actively pursuing non-dilutive funding opportunities, including grants, and may seek institutional or bank financing to bolster its financial position. The company remains focused on its long-term goal of achieving profitable operations, although it acknowledges the challenges posed by its current cash burn rate and the need for additional financial resources.
About EXOZYMES INC.
eXoZymes Inc. develops cell-free biomanufacturing solutions using engineered enzymes called exozymes, enabled by AI and bioengineering. Its platform produces valuable chemicals for nutraceuticals, pharmaceuticals, and biofuels, offering sustainable, scalable alternatives to traditional petrochemical and synthetic biology methods. The company focuses on licensing, partnerships, and spinouts to commercialize its innovative biosolutions in the biomanufacturing industry.
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