Mustang Bio, Inc. reported a net loss of $153,000 for the first quarter of 2025, a significant decrease from the $5.2 million loss recorded in the same period of 2024. The company attributed this improvement to a reduction in operating expenses, which fell to $253,000 from $5.2 million year-over-year. This decline was primarily driven by a substantial decrease in research and development costs, which dropped from $3.8 million to $964,000, reflecting strategic decisions made in 2024, including workforce reductions and the termination of certain clinical trials.

As of March 31, 2025, Mustang Bio had cash and cash equivalents totaling $14.2 million, a notable increase from $6.8 million at the end of 2024. This financial boost was largely due to a successful public offering completed in February 2025, which generated approximately $6.8 million in net proceeds. The company also reported a significant reduction in total liabilities, which decreased to $11.3 million from $13.2 million at the end of the previous fiscal year. Mustang Bio's accumulated deficit stood at $396.9 million as of the end of the first quarter.

In terms of operational developments, Mustang Bio has been focusing on its CAR T therapy pipeline, which includes partnerships with leading research institutions such as the City of Hope and Fred Hutchinson Cancer Center. The company is advancing its product candidates, including MB-101 and MB-106, through clinical trials, with plans to initiate additional studies in 2026. However, the company has not yet generated any revenue from its product candidates, and there remains substantial doubt about its ability to continue as a going concern without raising additional capital.

Mustang Bio's strategic decisions have included the termination of its lease for the Plantation Street Facility and the sale of related equipment, which were aimed at preserving capital and reallocating resources towards clinical programs. The company is currently exploring options for further financing to support its ongoing development efforts, as it anticipates continued operating losses in the foreseeable future. The outlook remains cautious, with management emphasizing the need for additional funding to sustain operations and advance its product candidates through the regulatory approval process.

About MUSTANG BIO, INC.

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